The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families.

Murakami, Yoshiki; Toyoda, Hidenori; Tanaka, Masami; Kuroda, Masahiko; Harada, Yoshinori; Matsuda, Fumihiko; Tajima, Atsushi; Kosaka, Nobuyoshi; Ochiya, Takahiro; Shimotohno, Kunitada

doi:10.1371/journal.pone.0016081

Public

The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families.

Shared by NobleBlocks on Jan 24, 2011 • 12:00 AM UTC

Authors:

Yoshiki Murakami

Hidenori Toyoda

Masami Tanaka

Abstract

BACKGROUND: Chronic hepatitis C (CH) can develop into liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Liver fibrosis and HCC development are strongly correlated, but there is no effective treatment against fibrosis because the critical mechanism of progression of liver fibrosis is not fully...

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