Safety of thiopurines and anti-TNF-α drugs during pregnancy in patients with inflammatory bowel disease.

J Casanova, M; Chaparro, M; Domènech, E; Barreiro-de Acosta, M; Bermejo, F; Iglesias, E; Gomollón, F; Rodrigo, L; Calvet, X; Esteve, M; García-Planella, E; García-López, S; Taxonera, C; Calvo, M; López, M; Ginard, D; Gómez-García, M; Garrido, E; L Pérez-Calle, J; Beltrán, B; Piqueras, M; Saro, C; Botella, B; Dueñas, C; Ponferrada, A; Mañosa, M; García-Sánchez, V; Maté, J; P Gisbert, J

doi:10.1038/ajg.2012.430

Public

Safety of thiopurines and anti-TNF-α drugs during pregnancy in patients with inflammatory bowel disease.

Shared by NobleBlocks on Mar 1, 2013 • 12:00 AM UTC

Authors:

M J Casanova

M Chaparro

E Domènech

Abstract

OBJECTIVES: The safety of thiopurines and anti-tumor necrosis factor-α (TNF-α) drugs during pregnancy remains controversial, as the experience with these drugs in this situation is limited. Our aim is to assess the safety of thiopurines and anti-TNF-α drugs for the treatment of inflammatory bowel di...

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