Synthesis and structure of [(η6-p-cymene)Ru(2-anthracen-9-ylmethylene-N-ethylhydrazinecarbothioamide)Cl]Cl; biological evaluation, topoisomerase II inhibition and reaction with DNA and human serum albumin

Beckford, F.; Thessing, Jeffrey; Woods, J.; Didion, J.; Gerasimchuk, N.; González‐Sarrías, A.; Seeram, N.

doi:10.1039/c1mt00003a

Public

Synthesis and structure of [(η6-p-cymene)Ru(2-anthracen-9-ylmethylene-N-ethylhydrazinecarbothioamide)Cl]Cl; biological evaluation, topoisomerase II inhibition and reaction with DNA and human serum albumin

Shared by NobleBlocks on Feb 23, 2011 • 12:00 AM UTC

Authors:

F. Beckford

Jeffrey Thessing

J. Woods

Abstract

We have synthesized and evaluated the biological properties of a compound of the type [η6-p-cymene)Ru(EtATSC)Cl]Cl (1) where EtATSC = 2-anthracen-9-ylmethylene-N-ethylhydrazinecarbothioamide, a thiosemicarbazone. The complex has been characterized by elemental analysis, spectroscopically (NMR, UV-Vi...

Subject

Medicine

Chemistry

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!