Mixed-ligand copper(II)-phenolate complexes: effect of coligand on enhanced DNA and protein binding, DNA cleavage, and anticancer activity.

V, Rajendiran; R, Karthik; M, Palaniandavar; H, Stoeckli-Evans; VS, Periasamy; MA, Akbarsha; BS, Srinag; H, Krishnamurthy

doi:10.1021/ic700755p

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Mixed-ligand copper(II)-phenolate complexes: effect of coligand on enhanced DNA and protein binding, DNA cleavage, and anticancer activity.

Shared by NobleBlocks on Sep 5, 2007 • 12:00 AM UTC

Authors:

Rajendiran V

Karthik R

Palaniandavar M

Abstract

The copper(II) complex [Cu(tdp)(ClO4)].0.5H2O (1), where H(tdp) is the tetradentate ligand 2-[(2-(2-hydroxyethylamino)ethylimino)methyl]phenol, and the mixed ligand complexes [Cu(tdp)(diimine)]+ (2-5), where diimine is 2,2'-bipyridine (bpy) (2), 1,10-phenanthroline (phen) (3), 3,4,7,8-tetramethyl-1,...

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