We set out to ascertain the role of tachykinins, neurokinin A and substance P, in castor oil‐induced diarrhoea in rats as disclosed by the inhibitory effect of the non‐peptide NK 1 ‐ and NK 2 ‐receptor antagonists, SR 140333 and SR 48968, respectively. SR 48968 (0.02 to 20 μg kg −1 , s.c. or p.o.), ...
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