Recombinant urate oxidase (Rasburicase) for the treatment of hyperuricemia in pediatric patients with hematologic malignancies: Results of a compassionate prospective multicenter study in Korea.

HY, Shin; HJ, Kang; ES, Park; HS, Choi; HS, Ahn; SY, Kim; NG, Chung; HK, Kim; SY, Kim; H, Kook; TJ, Hwang; KC, Lee; SM, Lee; KS, Lee; KH, Yoo; HH, Koo; MJ, Lee; JJ, Seo; HN, Moon; T, Ghim; CJ, Lyu; WS, Lee; YM, Choi

doi:10.1002/pbc.20555

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Recombinant urate oxidase (Rasburicase) for the treatment of hyperuricemia in pediatric patients with hematologic malignancies: Results of a compassionate prospective multicenter study in Korea.

Shared by NobleBlocks on Apr 1, 2006 • 12:00 AM UTC

Authors:

Shin HY

Kang HJ

Park ES

Abstract

<h4>Background</h4>Hyperuricemia accompanying tumor lysis syndrome is a serious complication in neoplasia with rapid proliferation and destruction. To confirm the efficacy of recombinant urate oxidase (rasburicase) and its safety profile, a phase IV compassionate use prospective study was performed ...

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