Origin of myofibroblasts in the fibrotic liver in mice.

K, Iwaisako; C, Jiang; M, Zhang; M, Cong; TJ, Moore-Morris; TJ, Park; X, Liu; J, Xu; P, Wang; YH, Paik; F, Meng; M, Asagiri; LA, Murray; AF, Hofmann; T, Iida; CK, Glass; DA, Brenner; T, Kisseleva

doi:10.1073/pnas.1400062111

Public

Origin of myofibroblasts in the fibrotic liver in mice.

Shared by NobleBlocks on Jul 29, 2014 • 12:00 AM UTC

Authors:

Iwaisako K

Jiang C

Zhang M

Abstract

Hepatic myofibroblasts are activated in response to chronic liver injury of any etiology to produce a fibrous scar. Despite extensive studies, the origin of myofibroblasts in different types of fibrotic liver diseases is unresolved. To identify distinct populations of myofibroblasts and quantify the...

Subject

Ecm Deposition

Markers Of Fibrogenic Myofibroblasts

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