Multiple ascending dose study of BMS-790052, a nonstructural protein 5A replication complex inhibitor, in patients infected with hepatitis C virus genotype 1.

RE, Nettles; M, Gao; M, Bifano; E, Chung; A, Persson; TC, Marbury; R, Goldwater; MP, DeMicco; M, Rodriguez-Torres; A, Vutikullird; E, Fuentes; E, Lawitz; JC, Lopez-Talavera; DM, Grasela

doi:10.1002/hep.24609

Public

Multiple ascending dose study of BMS-790052, a nonstructural protein 5A replication complex inhibitor, in patients infected with hepatitis C virus genotype 1.

Shared by NobleBlocks on Dec 1, 2011 • 12:00 AM UTC

Authors:

Nettles RE

Gao M

Bifano M

Abstract

<h4>Unlabelled</h4>The antiviral activity, resistance profile, pharmacokinetics (PK), safety, and tolerability of BMS-790052, a nonstructural protein 5A (NS5A) replication complex inhibitor, were evaluated in a double-blind, placebo-controlled, sequential panel, multiple ascending dose study. Thirty...

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