Single-dose pharmacokinetics, safety, and tolerance of linopirdine (DuP 996) in healthy young adults and elderly volunteers.

J Pieniaszek, H; D Fiske, W; D Saxton, T; S Kim, Y; M Garner, D; Xilinas, M; Martz, R

doi:10.1002/j.1552-4604.1995.tb04741.x

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Single-dose pharmacokinetics, safety, and tolerance of linopirdine (DuP 996) in healthy young adults and elderly volunteers.

Shared by NobleBlocks on Jan 1, 1995 • 12:00 AM UTC

Authors:

H J Pieniaszek

W D Fiske

T D Saxton

Abstract

The pharmacokinetics, safety, and tolerance of linopiridine ([3,3-bis(4-pyridinylmethyl)-1-phenylindolin-2-one]; DuP 996) a potential therapeutic agent for Alzheimer's disease, were assessed in double-blind, placebo-controlled, randomized studies in which single oral doses were given to 64 healthy y...

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