Secondary genetic lesions in acute myeloid leukemia with inv(16) or t(16;16): a study of the German-Austrian AML Study Group (AMLSG)

Paschka, Peter; Du, Juan; F. Schlenk, Richard; I. Gaidzik, Verena; Bullinger, Lars; Corbacioglu, Andrea; Späth, Daniela; Kayser, Sabine; Schlegelberger, Brigitte; Krauter, Jürgen; Ganser, Arnold; Köhne, Claus-Henning; Held, Gerhard; von Lilienfeld-Toal, Marie; Kirchen, Heinz; Rummel, Mathias; Götze, Katharina; Horst, Heinz-August; Ringhoffer, Mark; Lübbert, Michael; Wattad, Mohammed; R. Salih, Helmut; Kündgen, Andrea; Döhner, Hartmut; Döhner, Konstanze

doi:10.1182/blood-2012-05-431486

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Secondary genetic lesions in acute myeloid leukemia with inv(16) or t(16;16): a study of the German-Austrian AML Study Group (AMLSG)

Published in Blood • Jan 3, 2013

Authors:

Peter Paschka

Juan Du

Richard F. Schlenk

Abstract

Abstract In this study, we evaluated the impact of secondary genetic lesions in acute myeloid leukemia (AML) with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11. We studied 176 patients, all enrolled on prospective treatment trials, for secondary chromosomal aberrations and mutations in N-/KRA...

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