Essential role of TRPC6 channels in G2/M phase transition and development of human glioma.

<h4>Background</h4>Patients with glioblastoma multiforme, the most aggressive form of glioma, have a median survival of approximately 12 months. Calcium (Ca(2+)) signaling plays an important role in cell proliferation, and some members of the Ca(2+)-permeable transient receptor potential canonical (... View More