Hypoxic preconditioning enhances the therapeutic potential of the secretome from cultured human mesenchymal stem cells in experimental traumatic brain injury.

CP, Chang; CC, Chio; CU, Cheong; CM, Chao; BC, Cheng; MT, Lin

doi:10.1042/cs20120226

Public

Hypoxic preconditioning enhances the therapeutic potential of the secretome from cultured human mesenchymal stem cells in experimental traumatic brain injury.

Shared by NobleBlocks on Feb 1, 2013 • 12:00 AM UTC

Authors:

Chang CP

Chio CC

Cheong CU

Abstract

Bone-marrow-derived human MSCs (mesenchymal stem cells) support repair when administered to animals with TBI (traumatic brain injury) in large part through secreted trophic factors. We directly tested the ability of the culture medium (or secretome) collected from human MSCs under normoxic or hypoxi...

Discussions