Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4.

H, Peng; V, Wright; A, Usas; B, Gearhart; HC, Shen; J, Cummins; J, Huard

doi:10.1172/jci15153

Public

Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4.

Shared by NobleBlocks on Sep 1, 2002 • 12:00 AM UTC

Authors:

Peng H

Wright V

Usas A

Abstract

We investigated the interaction between angiogenic and osteogenic factors in bone formation and bone healing with ex vivo gene therapy using muscle-derived stem cells genetically engineered to express human bone morphogenetic protein-4 (BMP4), VEGF, or VEGF-specific antagonist (soluble Flt1). Our re...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!