Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo.

M, Björndahl; R, Cao; LJ, Nissen; S, Clasper; LA, Johnson; Y, Xue; Z, Zhou; D, Jackson; AJ, Hansen; Y, Cao

doi:10.1073/pnas.0507865102

Public

Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo.

Shared by NobleBlocks on Oct 17, 2005 • 12:00 AM UTC

Authors:

Björndahl M

Cao R

Nissen LJ

Abstract

Lymphangiogenesis is an important process that contributes to the spread of cancer. Here we show that insulin-like growth factors 1 (IGF-1) and 2 (IGF-2) induce lymphangiogenesis in vivo. In a mouse cornea assay, IGF-1 and IGF-2 induce lymphangiogenesis as detected with LYVE-1, a specific marker for...

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