Reactive oxygen species-induced activation of ERK and p38 MAPK mediates PMA-induced NETs release from human neutrophils.

RS, Keshari; A, Verma; MK, Barthwal; M, Dikshit

doi:10.1002/jcb.24391

Public

Reactive oxygen species-induced activation of ERK and p38 MAPK mediates PMA-induced NETs release from human neutrophils.

Shared by NobleBlocks on Mar 1, 2013 • 12:00 AM UTC

Authors:

Keshari RS

Verma A

Barthwal MK

Abstract

Neutrophils/polymorphonuclear leukocytes (PMNs), an important component of innate immune system, release extracellular traps (NETs) to eliminate invaded pathogens; however understanding of the role of signaling molecules/proteins need to be elucidated. In the present study role of p38 MAPK and extra...

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