Microparticles carrying Sonic hedgehog favor neovascularization through the activation of nitric oxide pathway in mice.

<h4>Background</h4>Microparticles (MPs) are vesicles released from plasma membrane upon cell activation and during apoptosis. Human T lymphocytes undergoing activation and apoptosis generate MPs bearing morphogen Shh (MPs(Shh+)) that are able to regulate in vitro angiogenesis.<h4>Methodology/princip... View More