Adenosine deaminase alleles and autistic disorder: Case-control and family-based association studies

M. Persico, Antonio; Militerni, Roberto; Bravaccio, Carmela; Schneider, Cindy; D. Melmed, Raun; Trillo, Simona; Montecchi, Francesco; T. Palermo, Mark; Pascucci, Tiziana; Puglisi‐Allegra, Stefano; Reichelt, Karl-Ludvig; Conciatori, Monica; Baldi, Alfonso; Keller, Flavio

doi:10.1002/1096-8628(20001204)96:6<784::aid-ajmg18>3.0.co;2-7

Public

Adenosine deaminase alleles and autistic disorder: Case-control and family-based association studies

Shared by NobleBlocks on Jan 1, 2000 • 12:00 AM UTC

Authors:

Antonio M. Persico

Roberto Militerni

Carmela Bravaccio

Abstract

Adenosine deaminase (ADA) plays a relevant role in purine metabolism, immune responses, and peptidase activity, which may be altered in some autistic patients. Codominant ADA1 and ADA2 alleles code for ADA1 and ADA2 allozymes, the most frequent protein isoforms in the general population. Individuals...

Subject

Allele

Linkage disequilibrium

Genetics

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