Time-action profile of the soluble, fatty acid acylated, long-acting insulin analogue NN304.

L, Heinemann; K, Sinha; C, Weyer; M, Loftager; S, Hirschberger; T, Heise

doi:10.1046/j.1464-5491.1999.00081.x

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Time-action profile of the soluble, fatty acid acylated, long-acting insulin analogue NN304.

Shared by NobleBlocks on Apr 1, 1999 • 12:00 AM UTC

Authors:

Heinemann L

Sinha K

Weyer C

Abstract

<h4>Aims</h4>To compare the pharmacokinetic and pharmacodynamic properties of subcutaneously injected NN304, a novel long-acting insulin analogue, to NPH-insulin during euglycaemic glucose clamps in 11 healthy volunteers.<h4>Methods</h4>On three study days NN304 was injected in three different doses...

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