Possible role of the JAK/STAT pathways in the regulation of T cell-interferon related genes in systemic lupus erythematosus

Kawasaki, Maki; Fujishiro, Midori; Yamaguchi, Ayako; Nozawa, Kazuki; Kaneko, Hiroshi; Takasaki, Yoshinari; Takamori, Kenji; Ogawa, Hideoki; Sekigawa, Iwao

doi:10.1177/0961203311409963

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Possible role of the JAK/STAT pathways in the regulation of T cell-interferon related genes in systemic lupus erythematosus

Shared by NobleBlocks on Oct 1, 2011 • 12:00 AM UTC

Authors:

Maki Kawasaki

Midori Fujishiro

Ayako Yamaguchi

Abstract

Changes in gene expression in CD3+ T cells associated with disease progression in systemic lupus erythematosus (SLE) patients were determined. The genes related to SLE disease-related activities were identified and their gene regulatory networks were investigated. Analyses of gene expression were pe...

Subject

JAK-STAT signaling pathway

STAT protein

Janus kinase

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