Myositis-specific anti-155/140 autoantibodies target transcription intermediary factor 1 family proteins.

M, Fujimoto; Y, Hamaguchi; K, Kaji; T, Matsushita; Y, Ichimura; M, Kodera; N, Ishiguro; I, Ueda-Hayakawa; Y, Asano; F, Ogawa; K, Fujikawa; T, Miyagi; E, Mabuchi; K, Hirose; N, Akimoto; N, Hatta; K, Tsutsui; A, Higashi; A, Igarashi; M, Seishima; M, Hasegawa; K, Takehara

doi:10.1002/art.33403

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Myositis-specific anti-155/140 autoantibodies target transcription intermediary factor 1 family proteins.

Shared by NobleBlocks on Feb 1, 2012 • 12:00 AM UTC

Authors:

Fujimoto M

Hamaguchi Y

Kaji K

Abstract

<h4>Objective</h4>To identify the 140-kd autoantigen recognized by anti-155/140 autoantibodies that are associated with adult cancer-associated dermatomyositis (DM) and juvenile DM and to determine the clinical relevance of anti-155/140 antibodies in a large cohort.<h4>Methods</h4>Sera from 456 DM p...

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