The nonpsychotropic cannabinoid cannabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function.

J, Ahrens; R, Demir; M, Leuwer; la Roche J, de; K, Krampfl; N, Foadi; M, Karst; G, Haeseler

doi:10.1159/000201556

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The nonpsychotropic cannabinoid cannabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function.

Shared by NobleBlocks on Feb 10, 2009 • 12:00 AM UTC

Authors:

Ahrens J

Demir R

Leuwer M

Abstract

Loss of inhibitory synaptic transmission within the dorsal horn of the spinal cord plays a key role in the development of chronic pain following inflammation or nerve injury. Inhibitory postsynaptic transmission in the adult spinal cord involves mainly glycine. Cannabidiol is a nonpsychotropic plant...

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