Genome-wide screening for gene function using RNAi in mammalian cells.

LM, Cullen; GM, Arndt

doi:10.1111/j.1440-1711.2005.01332.x

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Genome-wide screening for gene function using RNAi in mammalian cells.

Shared by NobleBlocks on Jun 1, 2005 • 12:00 AM UTC

Authors:

Cullen LM

Arndt GM

Abstract

Mammalian genome sequencing has identified numerous genes requiring functional annotation. The discovery that dsRNA can direct gene-specific silencing in both model organisms and mammalian cells through RNA interference (RNAi) has provided a platform for dissecting the function of independent genes....

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