Curcumin enhances neurogenesis and cognition in aged rats: implications for transcriptional interactions related to growth and synaptic plasticity.

Dong, Suzhen; Zeng, Qingwen; Siobhan Mitchell, E; Xiu, Jin; Duan, Yale; Li, Chunxia; K Tiwari, Jyoti; Hu, Yinghe; Cao, Xiaohua; Zhao, Zheng

doi:10.1371/journal.pone.0031211

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Curcumin enhances neurogenesis and cognition in aged rats: implications for transcriptional interactions related to growth and synaptic plasticity.

Shared by NobleBlocks on Jan 1, 2012 • 12:00 AM UTC

Authors:

Suzhen Dong

Qingwen Zeng

E Siobhan Mitchell

Abstract

BACKGROUND: Curcumin has been demonstrated to have many neuroprotective properties, including improvement of cognition in humans and neurogenesis in animals, yet the mechanism of such effects remains unclear. METHODOLOGY: We assessed behavioural performance and hippocampal cell proliferation in aged...

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