Improved neuroprotective effects of resveratrol-loaded polysorbate 80-coated poly(lactide) nanoparticles in MPTP-induced Parkinsonism.

Rocha Lindner G, da; Santos D, Bonfanti; D, Colle; Moreira EL, Gasnhar; Prediger R, Daniel; M, Farina; NM, Khalil; Mainardes R, Mara

doi:10.2217/nnm.14.165

Public

Improved neuroprotective effects of resveratrol-loaded polysorbate 80-coated poly(lactide) nanoparticles in MPTP-induced Parkinsonism.

Shared by NobleBlocks on Jan 1, 2015 • 12:00 AM UTC

Authors:

da Rocha Lindner G

Bonfanti Santos D

Colle D

Abstract

<h4>Aim</h4>This study investigated the neuroprotective effects of resveratrol (RVT)-loaded polysorbate 80 (PS80)-coated poly(lactide) nanoparticles in a mouse model of Parkinson's disease (PD), and compared these effects with those from bulk RVT.<h4>Methods</h4>C57BL/6 mice received for 15 days RVT...

Subject

Antioxidant

Nanoparticles

Resveratrol

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