Enhanced and coordinated in vivo expression of inflammatory cytokines and nitric oxide synthase by chondrocytes from patients with osteoarthritis.

C, Melchiorri; R, Meliconi; L, Frizziero; T, Silvestri; L, Pulsatelli; I, Mazzetti; RM, Borzì; M, Uguccioni; A, Facchini

doi:10.1002/1529-0131(199812)41:12<2165::aid-art11>3.0.co;2-o

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Enhanced and coordinated in vivo expression of inflammatory cytokines and nitric oxide synthase by chondrocytes from patients with osteoarthritis.

Shared by NobleBlocks on Dec 1, 1998 • 12:00 AM UTC

Authors:

Melchiorri C

Meliconi R

Frizziero L

Abstract

<h4>Objective</h4>To evaluate the sites of expression of interleukin-1beta (IL-1beta), tumor necrosis factor alpha (TNFalpha), and inducible nitric oxide synthase (iNOS) in patients with inflammatory and degenerative joint diseases.<h4>Methods</h4>Cytokines and iNOS were detected by immunohistochemi...

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