Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy.

L, Zhang; B, Ramratnam; K, Tenner-Racz; Y, He; M, Vesanen; S, Lewin; A, Talal; P, Racz; AS, Perelson; BT, Korber; M, Markowitz; DD, Ho

doi:10.1056/nejm199905273402101

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Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy.

Shared by NobleBlocks on May 1, 1999 • 12:00 AM UTC

Authors:

Zhang L

Ramratnam B

Tenner-Racz K

Abstract

Background In patients infected with human immunodeficiency virus type 1 (HIV-1), combination antiretroviral therapy can result in sustained suppression of plasma levels of the virus. However, replication-competent virus can still be recovered from latently infected resting memory CD4 lymphocytes; t...

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