Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre.

T, Takahashi; K, Fujihara; I, Nakashima; T, Misu; I, Miyazawa; M, Nakamura; S, Watanabe; Y, Shiga; C, Kanaoka; J, Fujimori; S, Sato; Y, Itoyama

doi:10.1093/brain/awm062

Public

Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre.

Shared by NobleBlocks on Apr 19, 2007 • 12:00 AM UTC

Authors:

Takahashi T

Fujihara K

Nakashima I

Abstract

NMO-IgG is a disease-specific autoantibody for neuromyelitis optica (NMO) and its target antigen is aquaporin-4 (AQP4) water channel. Recently, we established a sensitive anti-AQP4 antibody assay using human AQP4-transfected cells, which appeared more sensitive than the original NMO-IgG assay. So fa...

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