Skin nerve α-synuclein deposits: a biomarker for idiopathic Parkinson disease.

V, Donadio; A, Incensi; V, Leta; MP, Giannoccaro; C, Scaglione; P, Martinelli; S, Capellari; P, Avoni; A, Baruzzi; R, Liguori

doi:10.1212/wnl.0000000000000316

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Skin nerve α-synuclein deposits: a biomarker for idiopathic Parkinson disease.

Shared by NobleBlocks on Mar 14, 2014 • 12:00 AM UTC

Authors:

Donadio V

Incensi A

Leta V

Abstract

<h4>Objective</h4>To investigate (1) whether phosphorylated α-synuclein deposits in skin nerve fibers might represent a useful biomarker for idiopathic Parkinson disease (IPD), and (2) the underlying pathogenesis of peripheral neuropathy associated with IPD.<h4>Methods</h4>Twenty-one well-characteri...

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