B7-H3 is overexpressed in patients suffering osteosarcoma and associated with tumor aggressiveness and metastasis.

B7-H3 is a member of the B7-family of co-stimulatory molecules, which has been shown to be broadly expressed in various tumor tissues, and which plays an important role in adaptive immune responses. The role of B7-H3 in osteosarcoma, however, remains unknown. In this study we used immunohistochemist... View More