First‐trimester screening for trisomy 21 by free beta‐human chorionic gonadotropin and pregnancy‐associated plasma protein‐A: impact of maternal and pregnancy characteristics

Oliver Kagan, Karl; Wright, D.; Spencer, Kevin; S. Molina, Francisca; H. Nicolaides, K.

doi:10.1002/uog.5332

Public

First‐trimester screening for trisomy 21 by free beta‐human chorionic gonadotropin and pregnancy‐associated plasma protein‐A: impact of maternal and pregnancy characteristics

Published in Ultrasound in Obstetrics and Gynecology • Apr 23, 2008

Authors:

Karl Oliver Kagan

D. Wright

Kevin Spencer

Abstract

OBJECTIVES: To use multiple regression analysis to define the contribution of maternal variables that influence the measured concentration of free beta-human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein-A (PAPP-A), and the interaction between these covariates, in first-t...

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Open Access

Subject

Trisomy

Medicine

Pregnancy

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