Reversal of Rocuronium-induced Neuromuscular Blockade with Sugammadex in Pediatric and Adult Surgical Patients

Plaud, Benoît; Meretoja, Olli; Hofmockel, Rainer; Raft, Julien; A. Stoddart, Peter; H. M. van Kuijk, Jacqueline; Hermens, Yvonne; K. Mirakhur, Rajinder

doi:10.1097/aln.0b013e318194caaa

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Reversal of Rocuronium-induced Neuromuscular Blockade with Sugammadex in Pediatric and Adult Surgical Patients

Published in Anesthesiology • Feb 1, 2009

Authors:

Benoît Plaud

Olli Meretoja

Rainer Hofmockel

Abstract

Background Sugammadex reverses neuromuscular blockade by chemical encapsulation of rocuronium. This phase IIIA study explored efficacy and safety of sugammadex in infants (28 days to 23 months), children (2-11 yr), adolescents (12-17 yr), and adults (18-65 yr). Methods Anesthetized patients (America...

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