Transplantation of mesenchymal stem cells promotes an alternative pathway of macrophage activation and functional recovery after spinal cord injury.

Nakajima, Hideaki; Uchida, Kenzo; Rodriguez Guerrero, Alexander; Watanabe, Shuji; Sugita, Daisuke; Takeura, Naoto; Yoshida, Ai; Long, Guang; T Wright, Karina; E B Johnson, William; Baba, Hisatoshi

doi:10.1089/neu.2011.2109

Public

Transplantation of mesenchymal stem cells promotes an alternative pathway of macrophage activation and functional recovery after spinal cord injury.

Shared by NobleBlocks on May 20, 2012 • 12:00 AM UTC

Authors:

Hideaki Nakajima

Kenzo Uchida

Alexander Rodriguez Guerrero

Abstract

Mesenchymal stem cells (MSC) derived from bone marrow can potentially reduce the acute inflammatory response in spinal cord injury (SCI) and thus promote functional recovery. However, the precise mechanisms through which transplanted MSC attenuate inflammation after SCI are still unclear. The presen...

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