Safety and efficacy of saxagliptin in combination with submaximal sulphonylurea versus up-titrated sulphonylurea over 76 weeks.

AR, Chacra; GH, Tan; S, Ravichandran; J, List; R, Chen

doi:10.1177/1479164111404574

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Safety and efficacy of saxagliptin in combination with submaximal sulphonylurea versus up-titrated sulphonylurea over 76 weeks.

Shared by NobleBlocks on Apr 1, 2011 • 12:00 AM UTC

Authors:

Chacra AR

Tan GH

Ravichandran S

Abstract

To assess the long-term efficacy and safety of saxagliptin in patients with type 2 diabetes mellitus inadequately controlled on sulphonylurea monotherapy, 768 patients were randomised to saxagliptin 2.5 or 5 mg in combination with glyburide 7.5 mg versus placebo added to up-titrated glyburide over 7...

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