Micro-MR angiography of normal and intratumoral vessels in mice using dedicated intravascular MR contrast agents with high generation of polyamidoamine dendrimer core: reference to pharmacokinetic properties of dendrimer-based MR contrast agents.

H, Kobayashi; S, Kawamoto; T, Saga; N, Sato; A, Hiraga; J, Konishi; K, Togashi; MW, Brechbiel

doi:10.1002/jmri.10025

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Micro-MR angiography of normal and intratumoral vessels in mice using dedicated intravascular MR contrast agents with high generation of polyamidoamine dendrimer core: reference to pharmacokinetic properties of dendrimer-based MR contrast agents.

Shared by NobleBlocks on Dec 1, 2001 • 12:00 AM UTC

Authors:

Kobayashi H

Kawamoto S

Saga T

Abstract

Pharmacokinetic characteristics of intravascular macromolecular magnetic resonance imaging (MRI) contrast agents with polyamidoamine dendrimer cores smaller than generation-7 were previously studied in the literature. To evaluate the effects of greater hepatic uptake on the pharmacokinetics of the l...

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