Genetic evidence for high-altitude adaptation in Tibet.

TS, Simonson; Y, Yang; CD, Huff; H, Yun; G, Qin; DJ, Witherspoon; Z, Bai; FR, Lorenzo; J, Xing; LB, Jorde; JT, Prchal; R, Ge

doi:10.1126/science.1189406

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Genetic evidence for high-altitude adaptation in Tibet.

Shared by NobleBlocks on May 13, 2010 • 12:00 AM UTC

Authors:

Simonson TS

Yang Y

Huff CD

Abstract

Tibetans have lived at very high altitudes for thousands of years, and they have a distinctive suite of physiological traits that enable them to tolerate environmental hypoxia. These phenotypes are clearly the result of adaptation to this environment, but their genetic basis remains unknown. We repo...

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