A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease

Jessen, F.; Amariglio, R.; Boxtel, M.; Breteler, M.; Ceccaldi, M.; Chételat, G.; Dubois, B.; Dufouil, C.; Ellis, K.; Flier, W.; Glodzik, L.; Harten, A.; Leon, M.; McHugh, P.; Mielke, M.; Molinuevo, J.; Mosconi, Lisa; Osorio, R.; Perrotin, Audrey; Petersen, R.; Rabin, L.; Rami, L.; Reisberg, B.; Rentz, D.; Sachdev, P.; Sayette, V.; Saykin, A.; Scheltens, P.; Shulman, M.; Slavin, M.; Sperling, R.; Stewart, R.; Uspenskaya, O.; Vellas, B.; Visser, P.; Wagner, M.

doi:10.1016/j.jalz.2014.01.001

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A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease

Shared by NobleBlocks on May 2, 2014 • 12:00 AM UTC

Authors:

Frank Jessen

Rebecca E. Amariglio

Martin van Boxtel

Abstract

Abstract There is increasing evidence that subjective cognitive decline (SCD) in individuals with unimpaired performance on cognitive tests may represent the first symptomatic manifestation of Alzheimer's disease (AD). The research on SCD in early AD, however, is limited by the absence of common sta...

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