Influence of the stabilizer coating layer on the purification and freeze-drying of poly(D,L-lactic acid) nanoparticles prepared by an emulsion-diffusion technique.

Quintanar-Guerrero, D; Ganem-Quintanar, A; Allémann, E; Fessi, H; Doelker, E

doi:10.3109/02652049809006840

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Influence of the stabilizer coating layer on the purification and freeze-drying of poly(D,L-lactic acid) nanoparticles prepared by an emulsion-diffusion technique.

Shared by NobleBlocks on Jun 17, 2026 • 09:08 AM UTC

Authors:

D Quintanar-Guerrero

A Ganem-Quintanar

E Allémann

Abstract

In this study, the purification by cross-flow filtration (CFF) and freeze drying of poly(D,L-lactic acid) (PLA) nanoparticles prepared by an emulsion-diffusion technique using poly(vinyl alcohol) (PVAL) or poloxamer 188 (P-188) were investigated. The stability of the suspensions was correlated to th...

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