Functional evidence of atypical beta 3-adrenoceptors in the human colon using the beta 3-selective adrenoceptor antagonist, SR 59230A.

Ponti F, De; G, Gibelli; T, Croci; M, Arcidiaco; F, Crema; L, Manara

doi:10.1111/j.1476-5381.1996.tb15294.x

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Functional evidence of atypical beta 3-adrenoceptors in the human colon using the beta 3-selective adrenoceptor antagonist, SR 59230A.

Shared by NobleBlocks on Apr 1, 1996 • 12:00 AM UTC

Authors:

De Ponti F

Gibelli G

Croci T

Abstract

The role of beta 3-adrenoceptors in human colonic circular smooth muscle was assessed in vitro by use of the beta 3-selective antagonist SR 59230A. Isoprenaline, in the presence of the selective beta-adrenoceptor antagonists CGP 20712A (beta 1) and ICI 118551 (beta 2), both at 0.1 microM, concentrat...

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