Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development.

M, Eißmann; T, Gutschner; M, Hämmerle; S, Günther; M, Caudron-Herger; M, Groß; P, Schirmacher; K, Rippe; T, Braun; M, Zörnig; S, Diederichs

doi:10.4161/rna.21089

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Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development.

Published in RNA biology • Aug 1, 2012

Authors:

Eißmann M

Gutschner T

Hämmerle M

Abstract

The metastasis-associated lung adenocarcinoma transcript 1, MALAT1, is a long non-coding RNA (lncRNA) that has been discovered as a marker for lung cancer metastasis. It is highly abundant, its expression is strongly regulated in many tumor entities including lung adenocarcinoma and hepatocellular c...

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