A Novel Splice Site Associated Polymorphism in the Tuberous Sclerosis 2 (TSC2) Gene May Predispose to the Development of Sporadic Gangliogliomas

Platten, Michael; Meyer‐Puttlitz, Birgit; Blümcke, Ingmar; Waha, Andreas; K. Wolf, Helmut; M. Nöthen, Markus; N. Louis, David; R. Sampson, Julian; von Deimling, Andreas

doi:10.1097/00005072-199756070-00007

Public

A Novel Splice Site Associated Polymorphism in the Tuberous Sclerosis 2 (TSC2) Gene May Predispose to the Development of Sporadic Gangliogliomas

Shared by NobleBlocks on Jul 1, 1997 • 12:00 AM UTC

Authors:

Michael Platten

Birgit Meyer‐Puttlitz

Ingmar Blümcke

Abstract

The tuberous sclerosis 2 (TSC2) gene is thought to function as a growth suppressor in sporadic and TSC-associated hamartomas and tumors. Clusters of dysplastic glial cells are a common feature of cortical tubers and subependymal nodules in tuberous sclerosis patients. In an effort to identify TSC2 g...

Subject

Tuberous sclerosis

TSC2

TSC1

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!