Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial.

M Lavoie Smith, Ellen; Pang, Herbert; Cirrincione, Constance; Fleishman, Stewart; D Paskett, Electra; Ahles, Tim; R Bressler, Linda; E Fadul, Camilo; Knox, Chetaye; Le-Lindqwister, Nguyet; B Gilman, Paul; L Shapiro, Charles; for Clinical Trials in Oncology, Alliance

doi:10.1001/jama.2013.2813

Public

Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial.

Shared by NobleBlocks on Apr 3, 2013 • 12:00 AM UTC

Authors:

Ellen M Lavoie Smith

Herbert Pang

Constance Cirrincione

Abstract

IMPORTANCE: There are no known effective treatments for painful chemotherapy-induced peripheral neuropathy. OBJECTIVE: To determine the effect of duloxetine, 60 mg daily, on average pain severity. DESIGN, SETTING, AND PATIENTS: Randomized, double-blind, placebo-controlled crossover trial at 8 Nation...

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