Long-term human B cell lines dependent on interleukin-4 and antibody to CD40.

J, Banchereau; Paoli P, de; A, Vallé; E, Garcia; F, Rousset

doi:10.1126/science.1702555

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Long-term human B cell lines dependent on interleukin-4 and antibody to CD40.

Shared by NobleBlocks on Jan 1, 1991 • 12:00 AM UTC

Authors:

Banchereau J

de Paoli P

Vallé A

Abstract

CD40 is a 45- to 50-kilodalton transmembrane glycoprotein expressed on B lymphocytes, epithelial cells, and some carcinoma cell lines. Human resting B lymphocytes entered a state of sustained proliferation when incubated with both the mouse fibroblastic Ltk- cell line that had been transfected with ...

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