Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: Subanalyses of a phase III trial

Bruix, Jordi; Raoul, Jean-Luc; Sherman, Morris; Mazzaferro, Vincenzo; Bolondi, Luigi; Craxi, Antonio; R. Galle, Peter; Santoro, Armando; Beaugrand, Michel; Sangiovanni, Angelo; Porta, Camillo; Gerken, Guido; A. Marrero, Jorge; Nadel, Andrea; Shan, Michael; Moscovici, Marius; Voliotis, Dimitris; M. Llovet, Josep

doi:10.1016/j.jhep.2012.06.014

Public

Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: Subanalyses of a phase III trial ,

Shared by NobleBlocks on Jun 19, 2012 • 12:00 AM UTC

Authors:

J. Bruix

J. Raoul

M. Sherman

Abstract

Background & Aims: The Sorafenib Hepatocellular Carcinoma (HCC) Assessment Randomized Protocol (SHARP) trial demonstrated that sorafenib improves overall survival and is safe for patients with advanced HCC. In this trial, 602 patients with well-preserved liver function (>95% Child–Pugh A) were rando...

Subject

Medicine

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