Avidin-dendrimer-(1B4M-Gd)(254): a tumor-targeting therapeutic agent for gadolinium neutron capture therapy of intraperitoneal disseminated tumor which can be monitored by MRI.

H, Kobayashi; S, Kawamoto; T, Saga; N, Sato; T, Ishimori; J, Konishi; K, Ono; K, Togashi; MW, Brechbiel

doi:10.1021/bc010002o

Public

Avidin-dendrimer-(1B4M-Gd)(254): a tumor-targeting therapeutic agent for gadolinium neutron capture therapy of intraperitoneal disseminated tumor which can be monitored by MRI.

Shared by NobleBlocks on Jul 1, 2001 • 12:00 AM UTC

Authors:

Kobayashi H

Kawamoto S

Saga T

Abstract

Peritoneal carcinomatosis is a late stage in cancer progress, for which no effective therapeutic modality exists. Targeting therapeutic agents to disseminated lesions may be a promising modality for treating peritoneal carcinomatosis. Gadolinium ((157,155)Gd) is known to generate Auger and internal ...

Discussions