Differential sensitivity of three experimental pain models in detecting the analgesic effects of transdermal fentanyl and buprenorphine.

Koltzenburg, Martin; Pokorny, Rolf; E Gasser, Urs; Richarz, Ute

doi:10.1016/j.pain.2006.06.028

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Differential sensitivity of three experimental pain models in detecting the analgesic effects of transdermal fentanyl and buprenorphine.

Shared by NobleBlocks on Dec 15, 2006 • 12:00 AM UTC

Authors:

Martin Koltzenburg

Rolf Pokorny

Urs E Gasser

Abstract

This is the first randomized controlled trial that tests the analgesic efficacy of transdermally delivered opioids in healthy volunteers and that assesses the sensitivity of different experimental pain tests to detect analgesia in this setting. Transdermal application of the full agonist fentanyl (T...

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