Use of the Membrane Invasion Culture System (MICS) as a screen for anti-invasive agents.

R Welch, D; J Lobl, T; A Seftor, E; J Wack, P; A Aeed, P; H Yohem, K; E Seftor, R; J Hendrix, M

doi:10.1002/ijc.2910430318

Public

Use of the Membrane Invasion Culture System (MICS) as a screen for anti-invasive agents.

Shared by NobleBlocks on Mar 15, 1989 • 12:00 AM UTC

Authors:

D R Welch

T J Lobl

E A Seftor

Abstract

The Membrane Invasion Culture System (MICS) assay was adapted for relatively rapid screening of compounds and used to identify anti-invasive drugs that inhibit human and murine tumor cell migration through a reconstituted basement membrane in vitro. Cell lines demonstrating low and high invasive and...

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