MicroRNA related polymorphisms and breast cancer risk.

S, Khan; D, Greco; K, Michailidou; RL, Milne; TA, Muranen; T, Heikkinen; K, Aaltonen; J, Dennis; MK, Bolla; J, Liu; P, Hall; A, Irwanto; K, Humphreys; J, Li; K, Czene; J, Chang-Claude; R, Hein; A, Rudolph; P, Seibold; D, Flesch-Janys; O, Fletcher; J, Peto; Santos Silva I, dos; N, Johnson; L, Gibson; Z, Aitken; JL, Hopper; H, Tsimiklis; M, Bui; E, Makalic; DF, Schmidt; MC, Southey; C, Apicella; J, Stone; Q, Waisfisz; H, Meijers-Heijboer; MA, Adank; der Luijt RB, van; A, Meindl; RK, Schmutzler; B, Müller-Myhsok; P, Lichtner; C, Turnbull; N, Rahman; SJ, Chanock; DJ, Hunter; A, Cox; SS, Cross; MW, Reed; MK, Schmidt; A, Broeks; Veer LJ, Van't; FB, Hogervorst; PA, Fasching; MG, Schrauder; AB, Ekici; MW, Beckmann; SE, Bojesen; BG, Nordestgaard; SF, Nielsen; H, Flyger; J, Benitez; PM, Zamora; JI, Perez; CA, Haiman; BE, Henderson; F, Schumacher; Marchand L, Le; PD, Pharoah; AM, Dunning; M, Shah; R, Luben; J, Brown; FJ, Couch; X, Wang; C, Vachon; JE, Olson; D, Lambrechts; M, Moisse; R, Paridaens; MR, Christiaens; P, Guénel; T, Truong; P, Laurent-Puig; C, Mulot; F, Marme; B, Burwinkel; A, Schneeweiss; C, Sohn; EJ, Sawyer; I, Tomlinson; MJ, Kerin; N, Miller; IL, Andrulis; JA, Knight; S, Tchatchou; AM, Mulligan; T, Dörk; NV, Bogdanova; NN, Antonenkova; H, Anton-Culver; H, Darabi; M, Eriksson; M, Garcia-Closas; J, Figueroa; J, Lissowska; L, Brinton; P, Devilee; RA, Tollenaar; C, Seynaeve; Asperen CJ, van; VN, Kristensen; S, Slager; AE, Toland; CB, Ambrosone; D, Yannoukakos; A, Lindblom; S, Margolin; P, Radice; P, Peterlongo; M, Barile; P, Mariani; MJ, Hooning; JW, Martens; JM, Collée; A, Jager; A, Jakubowska; J, Lubinski; K, Jaworska-Bieniek; K, Durda; GG, Giles; C, McLean; H, Brauch; T, Brüning; YD, Ko; H, Brenner; AK, Dieffenbach; V, Arndt; C, Stegmaier; A, Swerdlow; A, Ashworth; N, Orr; M, Jones; J, Simard; MS, Goldberg; F, Labrèche; M, Dumont; R, Winqvist; K, Pylkäs; A, Jukkola-Vuorinen; M, Grip; V, Kataja; VM, Kosma; JM, Hartikainen; A, Mannermaa; U, Hamann; G, Chenevix-Trench; C, Blomqvist; K, Aittomäki; DF, Easton; H, Nevanlinna

doi:10.1371/journal.pone.0109973

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MicroRNA related polymorphisms and breast cancer risk.

Shared by NobleBlocks on Nov 12, 2014 • 12:00 AM UTC

Authors:

Khan S

Greco D

Michailidou K

Abstract

Genetic variations, such as single nucleotide polymorphisms (SNPs) in microRNAs (miRNA) or in the miRNA binding sites may affect the miRNA dependent gene expression regulation, which has been implicated in various cancers, including breast cancer, and may alter individual susceptibility to cancer. W...

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