Local irradiation not only induces homing of human mesenchymal stem cells at exposed sites but promotes their widespread engraftment to multiple organs: a study of their quantitative distribution after irradiation damage.

S, François; M, Bensidhoum; M, Mouiseddine; C, Mazurier; B, Allenet; A, Semont; J, Frick; A, Saché; S, Bouchet; D, Thierry; P, Gourmelon; NC, Gorin; A, Chapel

doi:10.1634/stemcells.2005-0260

Public

Local irradiation not only induces homing of human mesenchymal stem cells at exposed sites but promotes their widespread engraftment to multiple organs: a study of their quantitative distribution after irradiation damage.

Shared by NobleBlocks on Dec 8, 2005 • 12:00 AM UTC

Authors:

François S

Bensidhoum M

Mouiseddine M

Abstract

Mesenchymal stem cells (MSCs) have been shown to migrate to various tissues. There is little information on the fate and potential therapeutic efficacy of the reinfusion of MSCs following total body irradiation (TBI). We addressed this question using human MSC (hMSCs) infused to nonobese diabetic/ s...

Discussions