A Ca2+-activated protease possibly involved in myofibrillar protein turnover. Partial characterization of the purified enzyme.

R Dayton, W; J Reville, W; E Goll, D; H Stromer, M

doi:10.1021/bi00655a020

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A Ca2+-activated protease possibly involved in myofibrillar protein turnover. Partial characterization of the purified enzyme.

Shared by NobleBlocks on May 18, 1976 • 12:00 AM UTC

Authors:

W R Dayton

W J Reville

D E Goll

Abstract

The purified Ca2+-activated protease (CAF) isolated from porcine skeletal muscle and capable of removing Z-disks from intact myofibrils is optimally active on either myofibril or casein substrates at pH 7.5 and in the presence of 1 mM Ca2+ and at least 2 mM 2-mercaptoethanol. No CAF activity is dete...

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