A new rabies vaccine based on a recombinant ORF virus (parapoxvirus) expressing the rabies virus glycoprotein.

R, Amann; J, Rohde; U, Wulle; D, Conlee; R, Raue; O, Martinon; HJ, Rziha

doi:10.1128/jvi.02470-12

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A new rabies vaccine based on a recombinant ORF virus (parapoxvirus) expressing the rabies virus glycoprotein.

Shared by NobleBlocks on Nov 21, 2012 • 12:00 AM UTC

Authors:

Amann R

Rohde J

Wulle U

Abstract

The present study describes the generation of a new Orf virus (ORFV) recombinant, D1701-V-RabG, expressing the rabies virus (RABV) glycoprotein that is correctly presented on the surface of infected cells without the need of replication or production of infectious recombinant virus. One single immun...

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